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Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians

机译:进行性黄斑部色素沉着病:高加索人很少诊断为色素沉着

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摘要

A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.
机译:一名35岁的妇女在12岁时在躯干和四肢上出现发白斑,并且在29岁和32岁怀孕后观察到色素沉着病变的明显增加。由于具有高度特征性的临床方面以及光镜和电镜的组织病理学发现,我们诊断为进行性黄斑部黑色素变性症(PMH)。它是一种非鳞屑性疾病,主要在躯干上有色素沉着的黄斑,在年轻女性中更常见。与某些作者假设丙酸杆菌属存在相反。作为PMH的一项原则问题,我们报告了没有丙酸杆菌属的证据。

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